![]() ![]() ![]() Rather than taking wide aim at the immune system, the drug blocks a specific protein that produces antibodies which, in lupus, can mistakenly attack the joints, skin, and other organs. It was approved to treat children with lupus in 2019 and to treat lupus nephritis in 2020. Belimumab (Benlysta)īelimumab was approved to treat lupus in adults in 2011. Talk to your doctor before getting any vaccines or if you are pregnant, may become pregnant, or are breastfeeding. Long-term use of azathioprine can increase the risk of cancer. Certain blood pressure medications including the ACE inhibitors Accupril and Vasotec.Allopurinol (Aloprim, Zyloprim) for gout.The full effect often takes 12 weeks to kick in. It works by stopping the spread of white blood cells.Īzathioprine is taken as a pill once a day. Anifrolumab may increase the risk of cancer.Īzathioprine reduces joint symptoms and damage and helps people who have lupus that affects their livers and kidneys. Talk to your doctor before getting a live vaccine and if you are pregnant, want to become pregnant, or are breastfeeding. Like other immunosuppressives, anifrolumab can increase the risk of infections. Most adults with lupus have elevated levels of type 1 interferons.Īnifrolumab is given as a 30-minute infusion once every 4 weeks in a medical facility.Īccording to the FDA, potential drug interactions haven't been formally studied. Anifrolumab holds down a type of immune-system compound called type 1 interferons. But it hasn’t been evaluated for lupus nephritis or lupus that affects the central nervous system. Research has shown that it can improve arthritis and skin rashes. The main immunosuppressant drugs used to treat lupus are: Anifrolumab (Saphnelo)Īnifrolumab was approved in 2021 to treat moderate to severe lupus in adults. The exact drugs your doctor prescribes will depend on how serious your disease is and what your symptoms are. Some of the most important of these drugs are called immunosuppressants, which work by dialing down your overactive immune system. Although there’s no cure, many drugs can treat symptoms caused by inflammation in lupus and even prevent permanent damage. Systemic lupus erythematosus (SLE) is an autoimmune disease that happens when your immune system mistakenly attacks different parts of your body, like your skin, joints, kidneys, heart, lungs, and brain. ![]()
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